Returning: Master Hand, Crazy Hand, Giga Bowser, Petey Piranha, Porky, Rayquaza, Galleom, The Yellow Devil, Metal Face, Dark Emperor, Master Core, Rathalos, Marx, Dracula, Ganon
New: King Boo, Ghastly King, Gohma, Dark Matter, Eternatus, Giygas, Hades, Metal Gear REX, Sigma, Amalthus, Kefka, Death, Adam Kon, Calasmos, Verse, Enderdragon, Ogre
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